Attenuation of Microglial Activation and Pyroptosis by Inhibition of P2X7 Pathway Promotes Photoreceptor Survival in Experimental Retinal Detachment

PURPOSE: Photoreceptor (PR) death is the ultimate cause of irreversible vision loss in retinal detachment (RD). Although microglial infiltration in the subretinal space (SRS) was observed after RD, the molecular mechanism underlying microglial activation and the outcomes of infiltrating microglia re...

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Detalles Bibliográficos
Autores principales: Cao, Manjing, Huang, Xinting, Zou, Jingling, Peng, Yingqian, Wang, Yanbing, Zheng, Xichen, Tang, Luosheng, Zhang, Lusi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Retinal Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292671/
https://www.ncbi.nlm.nih.gov/pubmed/37351878
http://dx.doi.org/10.1167/iovs.64.7.34

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