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Baseline malarial and nutritional profile of children under seasonal malaria chemoprevention coverage in the health district of Nanoro, Burkina Faso

Seasonal Malaria chemoprevention (SMC) is one of the large-scale life-saving malaria interventions initially recommended for the Sahel subregion, including Burkina Faso and recently extended to other parts of Africa. Initially, SMC was restricted to children 3 to 59 months old, but an extension to o...

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Autores principales: Sondo, Paul, Rouamba, Toussaint, Tahita, Marc Christian, Derra, Karim, Kabore, Berenger, Tibiri, Yssimini Nadège Guillène, Kabore, Hyacinthe Abd-El Latif Faïçal, Hien, So-vii Franck, Ouedraogo, Florence, Kazienga, Adama, Ilboudo, Hamidou, Rouamba, Eli, Lefevre, Thiery, Tinto, Halidou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292698/
https://www.ncbi.nlm.nih.gov/pubmed/37363896
http://dx.doi.org/10.1371/journal.pone.0287210
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author Sondo, Paul
Rouamba, Toussaint
Tahita, Marc Christian
Derra, Karim
Kabore, Berenger
Tibiri, Yssimini Nadège Guillène
Kabore, Hyacinthe Abd-El Latif Faïçal
Hien, So-vii Franck
Ouedraogo, Florence
Kazienga, Adama
Ilboudo, Hamidou
Rouamba, Eli
Lefevre, Thiery
Tinto, Halidou
author_facet Sondo, Paul
Rouamba, Toussaint
Tahita, Marc Christian
Derra, Karim
Kabore, Berenger
Tibiri, Yssimini Nadège Guillène
Kabore, Hyacinthe Abd-El Latif Faïçal
Hien, So-vii Franck
Ouedraogo, Florence
Kazienga, Adama
Ilboudo, Hamidou
Rouamba, Eli
Lefevre, Thiery
Tinto, Halidou
author_sort Sondo, Paul
collection PubMed
description Seasonal Malaria chemoprevention (SMC) is one of the large-scale life-saving malaria interventions initially recommended for the Sahel subregion, including Burkina Faso and recently extended to other parts of Africa. Initially, SMC was restricted to children 3 to 59 months old, but an extension to older children in some locations was recently recommended. Further characterization of SMC population profile beyond age criterion is necessary for understanding factors that could negatively impact the effectiveness of the intervention and to define complementary measures that could enhance its impact. Children were assessed through a cross-sectional survey during the first month of the 2020 SMC campaign (July-August 2020) as part of the SMC-NUT project in the health district of Nanoro. Parameters such as body temperature, weight, height, mid-upper arm circumference (MUAC) were assessed. In addition, blood sample was collected for malaria diagnosis by rapid diagnostic tests (RDT) and microscopy, and for haemoglobin measurement. A total of 1059 children were enrolled. RDT positivity rate (RPR) was 22.2%, while microscopy positivity rate (MPR) was 10.4%, with parasitaemia levels ranging from 40 to 70480/μL. RPR and MPR increased as patient age increased. Wasting was observed in 7.25% of children under SMC coverage while the prevalence of stunting and underweight was 48.79% and 23.38%, respectively. As the age of the children increased, an improvement in their nutritional status was observed. Finally, undernourished children had higher parasite densities than children with adequate nutritional status. In the health district of Nanoro, children who received Seasonal Malaria Chemoprevention (SMC) were mostly undernourished during the period of SMC delivery, suggesting the need for combining the SMC with synergistic interventions against malnutrition to achieve best impact.
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spelling pubmed-102926982023-06-27 Baseline malarial and nutritional profile of children under seasonal malaria chemoprevention coverage in the health district of Nanoro, Burkina Faso Sondo, Paul Rouamba, Toussaint Tahita, Marc Christian Derra, Karim Kabore, Berenger Tibiri, Yssimini Nadège Guillène Kabore, Hyacinthe Abd-El Latif Faïçal Hien, So-vii Franck Ouedraogo, Florence Kazienga, Adama Ilboudo, Hamidou Rouamba, Eli Lefevre, Thiery Tinto, Halidou PLoS One Research Article Seasonal Malaria chemoprevention (SMC) is one of the large-scale life-saving malaria interventions initially recommended for the Sahel subregion, including Burkina Faso and recently extended to other parts of Africa. Initially, SMC was restricted to children 3 to 59 months old, but an extension to older children in some locations was recently recommended. Further characterization of SMC population profile beyond age criterion is necessary for understanding factors that could negatively impact the effectiveness of the intervention and to define complementary measures that could enhance its impact. Children were assessed through a cross-sectional survey during the first month of the 2020 SMC campaign (July-August 2020) as part of the SMC-NUT project in the health district of Nanoro. Parameters such as body temperature, weight, height, mid-upper arm circumference (MUAC) were assessed. In addition, blood sample was collected for malaria diagnosis by rapid diagnostic tests (RDT) and microscopy, and for haemoglobin measurement. A total of 1059 children were enrolled. RDT positivity rate (RPR) was 22.2%, while microscopy positivity rate (MPR) was 10.4%, with parasitaemia levels ranging from 40 to 70480/μL. RPR and MPR increased as patient age increased. Wasting was observed in 7.25% of children under SMC coverage while the prevalence of stunting and underweight was 48.79% and 23.38%, respectively. As the age of the children increased, an improvement in their nutritional status was observed. Finally, undernourished children had higher parasite densities than children with adequate nutritional status. In the health district of Nanoro, children who received Seasonal Malaria Chemoprevention (SMC) were mostly undernourished during the period of SMC delivery, suggesting the need for combining the SMC with synergistic interventions against malnutrition to achieve best impact. Public Library of Science 2023-06-26 /pmc/articles/PMC10292698/ /pubmed/37363896 http://dx.doi.org/10.1371/journal.pone.0287210 Text en © 2023 Sondo et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Sondo, Paul
Rouamba, Toussaint
Tahita, Marc Christian
Derra, Karim
Kabore, Berenger
Tibiri, Yssimini Nadège Guillène
Kabore, Hyacinthe Abd-El Latif Faïçal
Hien, So-vii Franck
Ouedraogo, Florence
Kazienga, Adama
Ilboudo, Hamidou
Rouamba, Eli
Lefevre, Thiery
Tinto, Halidou
Baseline malarial and nutritional profile of children under seasonal malaria chemoprevention coverage in the health district of Nanoro, Burkina Faso
title Baseline malarial and nutritional profile of children under seasonal malaria chemoprevention coverage in the health district of Nanoro, Burkina Faso
title_full Baseline malarial and nutritional profile of children under seasonal malaria chemoprevention coverage in the health district of Nanoro, Burkina Faso
title_fullStr Baseline malarial and nutritional profile of children under seasonal malaria chemoprevention coverage in the health district of Nanoro, Burkina Faso
title_full_unstemmed Baseline malarial and nutritional profile of children under seasonal malaria chemoprevention coverage in the health district of Nanoro, Burkina Faso
title_short Baseline malarial and nutritional profile of children under seasonal malaria chemoprevention coverage in the health district of Nanoro, Burkina Faso
title_sort baseline malarial and nutritional profile of children under seasonal malaria chemoprevention coverage in the health district of nanoro, burkina faso
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292698/
https://www.ncbi.nlm.nih.gov/pubmed/37363896
http://dx.doi.org/10.1371/journal.pone.0287210
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