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How to increase noninvasive ventilation effectiveness in bulbar amyotrophic lateral sclerosis patients

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease in which the respiratory muscles are also affected, leading to respiratory failure. Bulbar impairment develops in almost all cases during the course of the disease, becoming severe in the late stages of disease. Noninvasi...

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Detalles Bibliográficos
Autores principales: Sancho, Jesus, Ferrer, Santos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292784/
https://www.ncbi.nlm.nih.gov/pubmed/37378058
http://dx.doi.org/10.1183/20734735.0266-2022
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author Sancho, Jesus
Ferrer, Santos
author_facet Sancho, Jesus
Ferrer, Santos
author_sort Sancho, Jesus
collection PubMed
description Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease in which the respiratory muscles are also affected, leading to respiratory failure. Bulbar impairment develops in almost all cases during the course of the disease, becoming severe in the late stages of disease. Noninvasive ventilation (NIV) has been shown to increase survival in ALS; however, severe bulbar dysfunction has a negative impact on NIV tolerance and effectiveness. Therefore, certain steps should be taken to improve NIV outcomes in these patients including optimal ventilatory parameters, adequate interface selection, effective respiratory secretion management and control of bulbar symptoms.
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spelling pubmed-102927842023-06-27 How to increase noninvasive ventilation effectiveness in bulbar amyotrophic lateral sclerosis patients Sancho, Jesus Ferrer, Santos Breathe (Sheff) Ask the Expert Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease in which the respiratory muscles are also affected, leading to respiratory failure. Bulbar impairment develops in almost all cases during the course of the disease, becoming severe in the late stages of disease. Noninvasive ventilation (NIV) has been shown to increase survival in ALS; however, severe bulbar dysfunction has a negative impact on NIV tolerance and effectiveness. Therefore, certain steps should be taken to improve NIV outcomes in these patients including optimal ventilatory parameters, adequate interface selection, effective respiratory secretion management and control of bulbar symptoms. European Respiratory Society 2023-03 2023-03-14 /pmc/articles/PMC10292784/ /pubmed/37378058 http://dx.doi.org/10.1183/20734735.0266-2022 Text en Copyright ©ERS 2023 https://creativecommons.org/licenses/by-nc/4.0/Breathe articles are open access and distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0.
spellingShingle Ask the Expert
Sancho, Jesus
Ferrer, Santos
How to increase noninvasive ventilation effectiveness in bulbar amyotrophic lateral sclerosis patients
title How to increase noninvasive ventilation effectiveness in bulbar amyotrophic lateral sclerosis patients
title_full How to increase noninvasive ventilation effectiveness in bulbar amyotrophic lateral sclerosis patients
title_fullStr How to increase noninvasive ventilation effectiveness in bulbar amyotrophic lateral sclerosis patients
title_full_unstemmed How to increase noninvasive ventilation effectiveness in bulbar amyotrophic lateral sclerosis patients
title_short How to increase noninvasive ventilation effectiveness in bulbar amyotrophic lateral sclerosis patients
title_sort how to increase noninvasive ventilation effectiveness in bulbar amyotrophic lateral sclerosis patients
topic Ask the Expert
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292784/
https://www.ncbi.nlm.nih.gov/pubmed/37378058
http://dx.doi.org/10.1183/20734735.0266-2022
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