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How to increase noninvasive ventilation effectiveness in bulbar amyotrophic lateral sclerosis patients
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease in which the respiratory muscles are also affected, leading to respiratory failure. Bulbar impairment develops in almost all cases during the course of the disease, becoming severe in the late stages of disease. Noninvasi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Respiratory Society
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292784/ https://www.ncbi.nlm.nih.gov/pubmed/37378058 http://dx.doi.org/10.1183/20734735.0266-2022 |
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author | Sancho, Jesus Ferrer, Santos |
author_facet | Sancho, Jesus Ferrer, Santos |
author_sort | Sancho, Jesus |
collection | PubMed |
description | Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease in which the respiratory muscles are also affected, leading to respiratory failure. Bulbar impairment develops in almost all cases during the course of the disease, becoming severe in the late stages of disease. Noninvasive ventilation (NIV) has been shown to increase survival in ALS; however, severe bulbar dysfunction has a negative impact on NIV tolerance and effectiveness. Therefore, certain steps should be taken to improve NIV outcomes in these patients including optimal ventilatory parameters, adequate interface selection, effective respiratory secretion management and control of bulbar symptoms. |
format | Online Article Text |
id | pubmed-10292784 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | European Respiratory Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-102927842023-06-27 How to increase noninvasive ventilation effectiveness in bulbar amyotrophic lateral sclerosis patients Sancho, Jesus Ferrer, Santos Breathe (Sheff) Ask the Expert Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease in which the respiratory muscles are also affected, leading to respiratory failure. Bulbar impairment develops in almost all cases during the course of the disease, becoming severe in the late stages of disease. Noninvasive ventilation (NIV) has been shown to increase survival in ALS; however, severe bulbar dysfunction has a negative impact on NIV tolerance and effectiveness. Therefore, certain steps should be taken to improve NIV outcomes in these patients including optimal ventilatory parameters, adequate interface selection, effective respiratory secretion management and control of bulbar symptoms. European Respiratory Society 2023-03 2023-03-14 /pmc/articles/PMC10292784/ /pubmed/37378058 http://dx.doi.org/10.1183/20734735.0266-2022 Text en Copyright ©ERS 2023 https://creativecommons.org/licenses/by-nc/4.0/Breathe articles are open access and distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. |
spellingShingle | Ask the Expert Sancho, Jesus Ferrer, Santos How to increase noninvasive ventilation effectiveness in bulbar amyotrophic lateral sclerosis patients |
title | How to increase noninvasive ventilation effectiveness in bulbar amyotrophic lateral sclerosis patients |
title_full | How to increase noninvasive ventilation effectiveness in bulbar amyotrophic lateral sclerosis patients |
title_fullStr | How to increase noninvasive ventilation effectiveness in bulbar amyotrophic lateral sclerosis patients |
title_full_unstemmed | How to increase noninvasive ventilation effectiveness in bulbar amyotrophic lateral sclerosis patients |
title_short | How to increase noninvasive ventilation effectiveness in bulbar amyotrophic lateral sclerosis patients |
title_sort | how to increase noninvasive ventilation effectiveness in bulbar amyotrophic lateral sclerosis patients |
topic | Ask the Expert |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292784/ https://www.ncbi.nlm.nih.gov/pubmed/37378058 http://dx.doi.org/10.1183/20734735.0266-2022 |
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