Reciprocal interactions between alveolar progenitor dysfunction and aging promote lung fibrosis

Aging is a critical risk factor in idiopathic pulmonary fibrosis (IPF). Dysfunction and loss of type 2 alveolar epithelial cells (AEC2s) with failed regeneration is a seminal causal event in the pathogenesis of IPF, although the precise mechanisms for their regenerative failure and demise remain unc...

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Detalles Bibliográficos
Autores principales: Liang, Jiurong, Huang, Guanling, Liu, Xue, Liu, Ningshan, Taghavifar, Forough, Dai, Kristy, Yao, Changfu, Deng, Nan, Wang, Yizhou, Chen, Peter, Hogaboam, Cory, Stripp, Barry R, Parks, William C, Noble, Paul W, Jiang, Dianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292844/
https://www.ncbi.nlm.nih.gov/pubmed/37314162
http://dx.doi.org/10.7554/eLife.85415

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