Unresectable metastatic colorectal cancer in fit patients – a practical algorithm of treatment sequencing from the Brazilian Group of Gastrointestinal Tumours (GTG)

Recent advances in biomarker-driven therapies have changed the landscape of unresectable metastatic colorectal cancer (mCRC) and brought not only access issues but also difficulties for the treating physician (especially generalist oncologists) in choosing the most suitable treatment for each indivi...

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Autores principales: Peixoto, Renata D’Alpino, Coutinho, Anelisa K, Prolla, Gabriel, Weschenfelder, Rui F, Riechelmann, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Intelligence 2023
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292853/
https://www.ncbi.nlm.nih.gov/pubmed/37377686
http://dx.doi.org/10.3332/ecancer.2023.1544
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author Peixoto, Renata D’Alpino
Coutinho, Anelisa K
Prolla, Gabriel
Weschenfelder, Rui F
Riechelmann, Rachel
author_facet Peixoto, Renata D’Alpino
Coutinho, Anelisa K
Prolla, Gabriel
Weschenfelder, Rui F
Riechelmann, Rachel
author_sort Peixoto, Renata D’Alpino
collection PubMed
description Recent advances in biomarker-driven therapies have changed the landscape of unresectable metastatic colorectal cancer (mCRC) and brought not only access issues but also difficulties for the treating physician (especially generalist oncologists) in choosing the most suitable treatment for each individual patient. This manuscript proposes an algorithm developed by The Brazilian Group of Gastrointestinal Tumours with the aim of bringing easy-to-follow steps in the management of unresectable mCRC. The algorithm is based on evidence for fit patients to facilitate therapeutic decisions in the clinical practice and assumes that there are no access and resource limitations.
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spelling pubmed-102928532023-06-27 Unresectable metastatic colorectal cancer in fit patients – a practical algorithm of treatment sequencing from the Brazilian Group of Gastrointestinal Tumours (GTG) Peixoto, Renata D’Alpino Coutinho, Anelisa K Prolla, Gabriel Weschenfelder, Rui F Riechelmann, Rachel Ecancermedicalscience Short Communication Recent advances in biomarker-driven therapies have changed the landscape of unresectable metastatic colorectal cancer (mCRC) and brought not only access issues but also difficulties for the treating physician (especially generalist oncologists) in choosing the most suitable treatment for each individual patient. This manuscript proposes an algorithm developed by The Brazilian Group of Gastrointestinal Tumours with the aim of bringing easy-to-follow steps in the management of unresectable mCRC. The algorithm is based on evidence for fit patients to facilitate therapeutic decisions in the clinical practice and assumes that there are no access and resource limitations. Cancer Intelligence 2023-05-02 /pmc/articles/PMC10292853/ /pubmed/37377686 http://dx.doi.org/10.3332/ecancer.2023.1544 Text en © the authors; licensee ecancermedicalscience. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Peixoto, Renata D’Alpino
Coutinho, Anelisa K
Prolla, Gabriel
Weschenfelder, Rui F
Riechelmann, Rachel
Unresectable metastatic colorectal cancer in fit patients – a practical algorithm of treatment sequencing from the Brazilian Group of Gastrointestinal Tumours (GTG)
title Unresectable metastatic colorectal cancer in fit patients – a practical algorithm of treatment sequencing from the Brazilian Group of Gastrointestinal Tumours (GTG)
title_full Unresectable metastatic colorectal cancer in fit patients – a practical algorithm of treatment sequencing from the Brazilian Group of Gastrointestinal Tumours (GTG)
title_fullStr Unresectable metastatic colorectal cancer in fit patients – a practical algorithm of treatment sequencing from the Brazilian Group of Gastrointestinal Tumours (GTG)
title_full_unstemmed Unresectable metastatic colorectal cancer in fit patients – a practical algorithm of treatment sequencing from the Brazilian Group of Gastrointestinal Tumours (GTG)
title_short Unresectable metastatic colorectal cancer in fit patients – a practical algorithm of treatment sequencing from the Brazilian Group of Gastrointestinal Tumours (GTG)
title_sort unresectable metastatic colorectal cancer in fit patients – a practical algorithm of treatment sequencing from the brazilian group of gastrointestinal tumours (gtg)
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292853/
https://www.ncbi.nlm.nih.gov/pubmed/37377686
http://dx.doi.org/10.3332/ecancer.2023.1544
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