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Knocking down NSUN5 inhibits the development of clear cell renal cell carcinoma by inhibiting the p53 pathway

Clear cell renal cell carcinoma (ccRCC) is the most common solid renal tumor. NSUN5, a gene encoding cytosine-5 RNA methyltransferase, has rarely been reported associated with cancer. A bioinformatics analysis revealed that NSUN5 was overexpressed in ccRCC. Gene Ontology and gene set variation analy...

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Detalles Bibliográficos
Autores principales: Li, Lei, Li, Mingyang, Zheng, Jianyi, Li, Zeyu, Chen, Xiaonan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292888/
https://www.ncbi.nlm.nih.gov/pubmed/37263638
http://dx.doi.org/10.18632/aging.204761