Cargando…

Knocking down NSUN5 inhibits the development of clear cell renal cell carcinoma by inhibiting the p53 pathway

Clear cell renal cell carcinoma (ccRCC) is the most common solid renal tumor. NSUN5, a gene encoding cytosine-5 RNA methyltransferase, has rarely been reported associated with cancer. A bioinformatics analysis revealed that NSUN5 was overexpressed in ccRCC. Gene Ontology and gene set variation analy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Lei, Li, Mingyang, Zheng, Jianyi, Li, Zeyu, Chen, Xiaonan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292888/ https://www.ncbi.nlm.nih.gov/pubmed/37263638 http://dx.doi.org/10.18632/aging.204761

Ejemplares similares

Prognostic Characteristics and Immune Effects of N(6)-Methyladenosine and 5-Methylcytosine-Related Regulatory Factors in Clear Cell Renal Cell Carcinoma
por: Li, Lei, et al.
Publicado: (2022)

Overview of distinct 5-methylcytosine profiles of messenger RNA in normal and knock-down NSUN2 colorectal cancer cells
por: Lin, Yu, et al.
Publicado: (2023)

Knocking down USP39 Inhibits the Growth and Metastasis of Non-Small-Cell Lung Cancer Cells through Activating the p53 Pathway
por: Yuan, Jiahui, et al.
Publicado: (2020)

Liquid biopsy at the frontier in renal cell carcinoma: recent analysis of techniques and clinical application
por: Li, Mingyang, et al.
Publicado: (2023)

Porcupine Inhibitor LGK974 Downregulates the Wnt Signaling Pathway and Inhibits Clear Cell Renal Cell Carcinoma
por: Li, Jianyi, et al.
Publicado: (2020)

Nomograms for predicting overall and cancer-specific survival of patients with chromophobe renal cell carcinoma after nephrectomy: a retrospective SEER-based study
por: Zheng, Jianyi, et al.
Publicado: (2022)

TRIM33 Overexpression Inhibits the Progression of Clear Cell Renal Cell Carcinoma In Vivo and In Vitro
por: Xu, Yingkun, et al.
Publicado: (2020)

The inhibition of invasion of human melanoma cells through N-cadherin knock-down
por: Ciołczyk-Wierzbicka, Dorota, et al.
Publicado: (2018)

RNA interference mediated pten knock-down inhibit the formation of polycystic ovary
por: Ouyang, Jie-Xiu, et al.
Publicado: (2013)

Knocking down LSD1 inhibits the stemness features of colorectal cancer stem cells
por: Chen, J., et al.
Publicado: (2020)

A united risk model of 11 immune‑related gene pairs and clinical stage for prediction of overall survival in clear cell renal cell carcinoma patients
por: Tao, Zijia, et al.
Publicado: (2021)

Rapid conditional knock-down–knock-in system for mammalian cells
por: Hölzel, Michael, et al.
Publicado: (2007)

MET Inhibition in Clear Cell Renal Cell Carcinoma
por: Xie, Zuoquan, et al.
Publicado: (2016)

Ubiquitin‐specific peptidase 53 inhibits the occurrence and development of clear cell renal cell carcinoma through NF‐κB pathway inactivation
por: Gui, Dingwen, et al.
Publicado: (2021)

Inhibition of miR‐34a‐5p can rescue disruption of the p53‐DAPK axis to suppress progression of clear cell renal cell carcinoma
por: Jing, Zhi‐Fei, et al.
Publicado: (2019)

Reorganization of the Landscape of Translated mRNAs in NSUN2-Deficient Cells and Specific Features of NSUN2 Target mRNAs
por: Kossinova, Olga A., et al.
Publicado: (2022)

Aloperine Inhibits Proliferation and Promotes Apoptosis in Colorectal Cancer Cells by Regulating the circNSUN2/miR-296-5p/STAT3 Pathway
por: Han, Wei, et al.
Publicado: (2021)

Analysis of genomes and transcriptomes of clear cell renal cell carcinomas identifies mutations and gene expression changes in the TGF-beta pathway
por: Che, Xiangyu, et al.
Publicado: (2022)

5-methylcytosine RNA methyltransferases and their potential roles in cancer
por: Li, Mingyang, et al.
Publicado: (2022)

p53 is functionally inhibited in clear cell renal cell carcinoma (ccRCC): a mechanistic and correlative investigation into genetic and molecular characteristics
por: Diesing, Karoline, et al.
Publicado: (2021)

ENAM gene associated with T classification and inhibits proliferation in renal clear cell carcinoma
por: Ren, Xiaohan, et al.
Publicado: (2021)

Knock-Down of Endogenous Bornavirus-Like Nucleoprotein 1 Inhibits Cell Growth and Induces Apoptosis in Human Oligodendroglia Cells
por: He, Peng, et al.
Publicado: (2016)

Ubiquitin-specific protease-44 inhibits the proliferation and migration of cells via inhibition of JNK pathway in clear cell renal cell carcinoma
por: Zhou, Jiangqiao, et al.
Publicado: (2020)

Knocking down gene expression for growth hormone-releasing hormone inhibits proliferation of human cancer cell lines
por: Barabutis, N, et al.
Publicado: (2008)

Inhibition of cancer migration and invasion by knocking down delta-5-desaturase in COX-2 overexpressed cancer cells
por: Yang, Xiaoyu, et al.
Publicado: (2017)

CLEC3B is downregulated and inhibits proliferation in clear cell renal cell carcinoma
por: Liu, Jian, et al.
Publicado: (2018)

MiR-506 Is Down-Regulated in Clear Cell Renal Cell Carcinoma and Inhibits Cell Growth and Metastasis via Targeting FLOT1
por: Yang, Feng-qiang, et al.
Publicado: (2015)

In leukemia, knock-down of the death inducer-obliterator gene would inhibit the proliferation of endothelial cells by inhibiting the expression of CDK6 and CCND1
por: Cao, Honghua, et al.
Publicado: (2022)

Claudin-2 inhibits renal clear cell carcinoma progression by inhibiting YAP-activation
por: Kumar, Balawant, et al.
Publicado: (2021)

The NSUN5-FTH1/FTL pathway mediates ferroptosis in bone marrow-derived mesenchymal stem cells
por: Liu, Jie, et al.
Publicado: (2022)

Pu-erh Tea Inhibits Tumor Cell Growth by Down-Regulating Mutant p53
por: Zhao, Lanjun, et al.
Publicado: (2011)

Knocking down of LINC01220 inhibits proliferation and induces apoptosis of endometrial carcinoma through silencing MAPK11
por: Li, Yong, et al.
Publicado: (2019)

MEIS1 inhibits clear cell renal cell carcinoma cells proliferation and in vitro invasion or migration
por: Zhu, Jie, et al.
Publicado: (2017)

LINC00152 Knock-down Suppresses Esophageal Cancer by EGFR Signaling Pathway
por: Ding, Yan, et al.
Publicado: (2020)

Correction: MiR-506 Is Down-Regulated in Clear Cell Renal Cell Carcinoma and Inhibits Cell Growth and Metastasis via Targeting FLOT1
por: Yang, Feng-qiang, et al.
Publicado: (2015)

Wnt2 knock down by RNAi inhibits the proliferation of in vitro-cultured human keloid fibroblasts
por: Cai, Yumei, et al.
Publicado: (2018)

Chemical Methods to Knock Down the Amyloid Proteins
por: Gao, Na, et al.
Publicado: (2017)

miR-93-3p inhibition suppresses clear cell renal cell carcinoma proliferation, metastasis and invasion
por: Wang, Lu, et al.
Publicado: (2017)

A New Prognostic Risk Model Based on PPAR Pathway-Related Genes in Kidney Renal Clear Cell Carcinoma
por: Xu, Yingkun, et al.
Publicado: (2020)

A New Survival Model Based on ADAMTSs for Prognostic Prediction in Clear Cell Renal Cell Carcinoma
por: Wu, Guangzhen, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_g4as8f8cg2tsi15t816e8ib7vm