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Impaired telomere pathway and fertility in Senescence-Accelerated Mice Prone 8 females with reproductive senescence

Ovarian aging is the main cause of infertility and telomere attrition is common to both aging and fertility disorders. Senescence-Accelerated Mouse Prone 8 (SAMP8) model has shortened lifespan and premature infertility, reflecting signs of reproductive senescence described in middle-aged women. Thus...

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Detalles Bibliográficos
Autores principales: Polonio, Alba M., Medrano, Marta, Chico-Sordo, Lucía, Córdova-Oriz, Isabel, Cozzolino, Mauro, Montans, José, Herraiz, Sonia, Seli, Emre, Pellicer, Antonio, García-Velasco, Juan A., Varela, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292900/
https://www.ncbi.nlm.nih.gov/pubmed/37338562
http://dx.doi.org/10.18632/aging.204731