CD38 marks the exhausted CD8(+) tissue-resident memory T cells in hepatocellular carcinoma

INTRODUCTION: Despite recent advances in immunotherapy for hepatocellular carcinoma (HCC), the overall modest response rate underscores the need for a better understanding of the tumor microenvironment (TME) of HCC. We have previously shown that CD38 is widely expressed on tumor-infiltrating leukocy...

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Detalles Bibliográficos
Autores principales: Reolo, Marie J. Y., Otsuka, Masayuki, Seow, Justine Jia Wen, Lee, Joycelyn, Lee, Yun Hua, Nguyen, Phuong H. D., Lim, Chun Jye, Wasser, Martin, Chua, Camillus, Lim, Tony K. H., Leow, Wei Qiang, Chung, Alexander, Goh, Brian K. P., Chow, Pierce K. H., DasGupta, Ramanuj, Yeong, Joe Poh Sheng, Chew, Valerie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292929/
https://www.ncbi.nlm.nih.gov/pubmed/37377962
http://dx.doi.org/10.3389/fimmu.2023.1182016

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