A Hepatitis B Virus Reactivation Case Potentially Triggered by the Onset of Diffuse Large B Cell Lymphoma

An 81-year-old man underwent rituximab-containing chemotherapy for chronic lymphocytic leukemia (CLL). Thirteen years after his last chemotherapy, he was diagnosed with hepatitis B virus (HBV) reactivation. He was then treated with entecavir, and improvement was seen in his liver injury. He develope...

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Autores principales: Sato, Kentaro, Imamura, Hidemichi, Watahiki, Yu, Hazama, Hiromasa, Hashimoto, Takeaki, Mukae, Shinji, Ohhira, Hiromasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293001/
https://www.ncbi.nlm.nih.gov/pubmed/36261374
http://dx.doi.org/10.2169/internalmedicine.0420-22
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author Sato, Kentaro
Imamura, Hidemichi
Watahiki, Yu
Hazama, Hiromasa
Hashimoto, Takeaki
Mukae, Shinji
Ohhira, Hiromasa
author_facet Sato, Kentaro
Imamura, Hidemichi
Watahiki, Yu
Hazama, Hiromasa
Hashimoto, Takeaki
Mukae, Shinji
Ohhira, Hiromasa
author_sort Sato, Kentaro
collection PubMed
description An 81-year-old man underwent rituximab-containing chemotherapy for chronic lymphocytic leukemia (CLL). Thirteen years after his last chemotherapy, he was diagnosed with hepatitis B virus (HBV) reactivation. He was then treated with entecavir, and improvement was seen in his liver injury. He developed diffuse large B cell lymphoma (DLBCL) after improvement in his hepatitis. Despite chemotherapy, he contracted the coronavirus disease 2019 (COVID-19) and died of COVID-19. We suspect that HBV reactivation was triggered by DLBCL. When HBV reactivation occurs a long time after chemotherapy has concluded, the onset of DLBCL should be considered.
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spelling pubmed-102930012023-06-28 A Hepatitis B Virus Reactivation Case Potentially Triggered by the Onset of Diffuse Large B Cell Lymphoma Sato, Kentaro Imamura, Hidemichi Watahiki, Yu Hazama, Hiromasa Hashimoto, Takeaki Mukae, Shinji Ohhira, Hiromasa Intern Med Case Report An 81-year-old man underwent rituximab-containing chemotherapy for chronic lymphocytic leukemia (CLL). Thirteen years after his last chemotherapy, he was diagnosed with hepatitis B virus (HBV) reactivation. He was then treated with entecavir, and improvement was seen in his liver injury. He developed diffuse large B cell lymphoma (DLBCL) after improvement in his hepatitis. Despite chemotherapy, he contracted the coronavirus disease 2019 (COVID-19) and died of COVID-19. We suspect that HBV reactivation was triggered by DLBCL. When HBV reactivation occurs a long time after chemotherapy has concluded, the onset of DLBCL should be considered. The Japanese Society of Internal Medicine 2022-10-19 2023-06-01 /pmc/articles/PMC10293001/ /pubmed/36261374 http://dx.doi.org/10.2169/internalmedicine.0420-22 Text en Copyright © 2023 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Sato, Kentaro
Imamura, Hidemichi
Watahiki, Yu
Hazama, Hiromasa
Hashimoto, Takeaki
Mukae, Shinji
Ohhira, Hiromasa
A Hepatitis B Virus Reactivation Case Potentially Triggered by the Onset of Diffuse Large B Cell Lymphoma
title A Hepatitis B Virus Reactivation Case Potentially Triggered by the Onset of Diffuse Large B Cell Lymphoma
title_full A Hepatitis B Virus Reactivation Case Potentially Triggered by the Onset of Diffuse Large B Cell Lymphoma
title_fullStr A Hepatitis B Virus Reactivation Case Potentially Triggered by the Onset of Diffuse Large B Cell Lymphoma
title_full_unstemmed A Hepatitis B Virus Reactivation Case Potentially Triggered by the Onset of Diffuse Large B Cell Lymphoma
title_short A Hepatitis B Virus Reactivation Case Potentially Triggered by the Onset of Diffuse Large B Cell Lymphoma
title_sort hepatitis b virus reactivation case potentially triggered by the onset of diffuse large b cell lymphoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293001/
https://www.ncbi.nlm.nih.gov/pubmed/36261374
http://dx.doi.org/10.2169/internalmedicine.0420-22
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