Case Report: Simultaneously Induced Neutropenia and Hemolysis After a Single Metamizole Dose

BACKGROUND AND OBJECTIVE: Metamizole is a non-opioid ampyrone sulfonate compound with potent analgesic, antipyretic, and spasmolytic effects. Agranulocytosis is a rare life-threatening complication of metamizole. CASE: Here, we present the case of a 62-year-old patient who developed agranulocytosis...

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Detalles Bibliográficos
Autores principales: Allgaier, Raphael, Kandulski, Arne, Gülow, Karsten, Maier, Lars, Müller, Martina, Tews, Hauke Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293139/
https://www.ncbi.nlm.nih.gov/pubmed/36988798
http://dx.doi.org/10.1007/s40268-023-00415-9
Descripción
Sumario:BACKGROUND AND OBJECTIVE: Metamizole is a non-opioid ampyrone sulfonate compound with potent analgesic, antipyretic, and spasmolytic effects. Agranulocytosis is a rare life-threatening complication of metamizole. CASE: Here, we present the case of a 62-year-old patient who developed agranulocytosis as well as hemolysis after a single administration of metamizole. CONCLUSION: This case illustrates the inherent allergic potential of metamizole and its effects on different hematopoietic cell types.

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