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Hypertrophic cardiomyopathy in purpose-bred cats with the A31P mutation in cardiac myosin binding protein-C

We sought to establish a large animal model of inherited hypertrophic cardiomyopathy (HCM) with sufficient disease severity and early penetrance for identification of novel therapeutic strategies. HCM is the most common inherited cardiac disorder affecting 1 in 250–500 people, yet few therapies for...

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Detalles Bibliográficos
Autores principales:	Stern, Joshua A., Rivas, Victor N., Kaplan, Joanna L., Ueda, Yu, Oldach, Maureen S., Ontiveros, Eric S., Kooiker, Kristina B., van Dijk, Sabine J., Harris, Samantha P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293195/ https://www.ncbi.nlm.nih.gov/pubmed/37365215 http://dx.doi.org/10.1038/s41598-023-36932-5

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