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Palmitic Acid Upregulates Type I Interferon–Mediated Antiviral Response and Cholesterol Biosynthesis in Human Astrocytes

Chronic intake of a high-fat diet increases saturated fatty acids in the brain causing the progression of neurodegenerative diseases. Palmitic acid is a free fatty acid abundant in the diet that at high concentrations may penetrate the blood–brain barrier and stimulate the production of pro-inflamma...

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Detalles Bibliográficos
Autores principales: Rojas-Cruz, Alexis Felipe, Martín-Jiménez, Cynthia Alexandra, González, Janneth, González-Giraldo, Yeimy, Pinzón, Andrés Mauricio, Barreto, George E., Aristizábal-Pachón, Andrés Felipe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293381/
https://www.ncbi.nlm.nih.gov/pubmed/37184765
http://dx.doi.org/10.1007/s12035-023-03366-z