Investigating the Synergistic Potential of Low-Dose HDAC3 Inhibition and Radiotherapy in Alzheimer’s Disease Models

We have previously shown that histone deacetylase (HDAC) inhibition and cranial radiotherapy (RT) independently improve molecular and behavioral Alzheimer’s disease (AD)-like phenotypes. In the present study, we investigate the synergistic potential of using both RT and HDACi as a low-dose combinati...

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Detalles Bibliográficos
Autores principales: Ricciardi, Natalie R., Modarresi, Farzaneh, Lohse, Ines, Andrade, Nadja S., Newman, Ian R., Brown, Jonathan M., Borja, Caroline, Marples, Brian, Wahlestedt, Claes R., Volmar, Claude-Henry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293392/
https://www.ncbi.nlm.nih.gov/pubmed/37171575
http://dx.doi.org/10.1007/s12035-023-03373-0

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