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Investigating the Synergistic Potential of Low-Dose HDAC3 Inhibition and Radiotherapy in Alzheimer’s Disease Models
We have previously shown that histone deacetylase (HDAC) inhibition and cranial radiotherapy (RT) independently improve molecular and behavioral Alzheimer’s disease (AD)-like phenotypes. In the present study, we investigate the synergistic potential of using both RT and HDACi as a low-dose combinati...
Autores principales: | Ricciardi, Natalie R., Modarresi, Farzaneh, Lohse, Ines, Andrade, Nadja S., Newman, Ian R., Brown, Jonathan M., Borja, Caroline, Marples, Brian, Wahlestedt, Claes R., Volmar, Claude-Henry |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293392/ https://www.ncbi.nlm.nih.gov/pubmed/37171575 http://dx.doi.org/10.1007/s12035-023-03373-0 |
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