Rat Hair Metabolomics Analysis Reveals Perturbations of Unsaturated Fatty Acid Biosynthesis, Phenylalanine, and Arachidonic Acid Metabolism Pathways Are Associated with Amyloid-β-Induced Cognitive Deficits

Hair is a noninvasive valuable biospecimen for the long-term assessment of endogenous metabolic disturbance. Whether the hair is suitable for identifying biomarkers of the Alzheimer’s disease (AD) process remains unknown. We aim to investigate the metabolism changes in hair after β-amyloid (Aβ(1-42)...

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Detalles Bibliográficos
Autores principales: Tan, Tian-Hoe, Li, Shih-Wen, Chang, Chih-Wei, Chen, Yuan-Chih, Liu, Yu-Hsuan, Ma, Jui-Ti, Chang, Ching-Ping, Liao, Pao-Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293421/
https://www.ncbi.nlm.nih.gov/pubmed/37095368
http://dx.doi.org/10.1007/s12035-023-03343-6

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