Phosphorylation of AKT by lysyl oxidase-like 2 activates the PI3K/AKT signaling pathway to promote proliferation, invasion and metastasis in esophageal squamous carcinoma

OBJECTIVE: Esophageal squamous cell carcinoma (ESCC) is a common and aggressive malignancy of the gastrointestinal tract for which therapeutic options are scarce. This study screens for LOXL2, a key gene in ESCC, and explains the molecular mechanism by which it promotes the progression of ESCC. METH...

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Detalles Bibliográficos
Autores principales: Fan, Zhiqin, Liu, Yingmin, Liu, Xinya, Nian, Wei, Huang, Xiaotong, Yang, Qianqian, Hou, Songyu, Chen, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293450/
https://www.ncbi.nlm.nih.gov/pubmed/36995521
http://dx.doi.org/10.1007/s12094-023-03133-5

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