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Thyroid Storm Masquerading as Multiple Organ Dysfunction Syndrome: Catch Me if You Can

A 65-year-old man presented to the emergency medicine department with altered sensorium, a high-grade fever, and shock. On routine workup, he was diagnosed with acute respiratory distress syndrome with sepsis. Later, it was found that the patient had undetectable serum thyroid stimulating hormone an...

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Autores principales: Khurana, Kashish, Kumar, Sunil, Acharya, Sourya, Toshniwal, Saket, Pantbalekundri, Nikhil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293479/
https://www.ncbi.nlm.nih.gov/pubmed/37384091
http://dx.doi.org/10.7759/cureus.39584
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author Khurana, Kashish
Kumar, Sunil
Acharya, Sourya
Toshniwal, Saket
Pantbalekundri, Nikhil
author_facet Khurana, Kashish
Kumar, Sunil
Acharya, Sourya
Toshniwal, Saket
Pantbalekundri, Nikhil
author_sort Khurana, Kashish
collection PubMed
description A 65-year-old man presented to the emergency medicine department with altered sensorium, a high-grade fever, and shock. On routine workup, he was diagnosed with acute respiratory distress syndrome with sepsis. Later, it was found that the patient had undetectable serum thyroid stimulating hormone and high triiodothyronine (T3) levels, which were diagnosed as a thyroid storm. This highlights the fact that a thyroid storm can present in any way and should be considered when determining the cause of septic shock that is not responding to standard treatment. A rare endocrine emergency, thyroid storm is a life-threatening endocrinological emergency with a considerable death rate of between 10% and 30% and multi-organ failure. It happens in thyrotoxic patients and manifests as the decompensation of several organs brought on by extreme stress. In addition to shock, the patient also had altered sensory perception, a cough, a fever, palpitations, and a sore throat. The patient was initially diagnosed with septic shock and was later treated with oral carbimazole, higher antibiotics, inotropes, and propranolol.
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spelling pubmed-102934792023-06-28 Thyroid Storm Masquerading as Multiple Organ Dysfunction Syndrome: Catch Me if You Can Khurana, Kashish Kumar, Sunil Acharya, Sourya Toshniwal, Saket Pantbalekundri, Nikhil Cureus Endocrinology/Diabetes/Metabolism A 65-year-old man presented to the emergency medicine department with altered sensorium, a high-grade fever, and shock. On routine workup, he was diagnosed with acute respiratory distress syndrome with sepsis. Later, it was found that the patient had undetectable serum thyroid stimulating hormone and high triiodothyronine (T3) levels, which were diagnosed as a thyroid storm. This highlights the fact that a thyroid storm can present in any way and should be considered when determining the cause of septic shock that is not responding to standard treatment. A rare endocrine emergency, thyroid storm is a life-threatening endocrinological emergency with a considerable death rate of between 10% and 30% and multi-organ failure. It happens in thyrotoxic patients and manifests as the decompensation of several organs brought on by extreme stress. In addition to shock, the patient also had altered sensory perception, a cough, a fever, palpitations, and a sore throat. The patient was initially diagnosed with septic shock and was later treated with oral carbimazole, higher antibiotics, inotropes, and propranolol. Cureus 2023-05-27 /pmc/articles/PMC10293479/ /pubmed/37384091 http://dx.doi.org/10.7759/cureus.39584 Text en Copyright © 2023, Khurana et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Khurana, Kashish
Kumar, Sunil
Acharya, Sourya
Toshniwal, Saket
Pantbalekundri, Nikhil
Thyroid Storm Masquerading as Multiple Organ Dysfunction Syndrome: Catch Me if You Can
title Thyroid Storm Masquerading as Multiple Organ Dysfunction Syndrome: Catch Me if You Can
title_full Thyroid Storm Masquerading as Multiple Organ Dysfunction Syndrome: Catch Me if You Can
title_fullStr Thyroid Storm Masquerading as Multiple Organ Dysfunction Syndrome: Catch Me if You Can
title_full_unstemmed Thyroid Storm Masquerading as Multiple Organ Dysfunction Syndrome: Catch Me if You Can
title_short Thyroid Storm Masquerading as Multiple Organ Dysfunction Syndrome: Catch Me if You Can
title_sort thyroid storm masquerading as multiple organ dysfunction syndrome: catch me if you can
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293479/
https://www.ncbi.nlm.nih.gov/pubmed/37384091
http://dx.doi.org/10.7759/cureus.39584
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