Cargando…
Factors associated with mortality after proximal femoral fracture
Proximal femoral fractures are a serious complication, especially for elderly patients. Therefore, we have aimed to answer the following research question: What is the postfracture mortality rate in the elderly population and what are associated risk factors? For this, proximal femoral fractures tha...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293507/ https://www.ncbi.nlm.nih.gov/pubmed/37365418 http://dx.doi.org/10.1186/s10195-023-00715-5 |
_version_ | 1785063010908241920 |
---|---|
author | Walter, Nike Szymski, Dominik Kurtz, Steve Alt, Volker Lowenberg, David W. Lau, Edmund Rupp, Markus |
author_facet | Walter, Nike Szymski, Dominik Kurtz, Steve Alt, Volker Lowenberg, David W. Lau, Edmund Rupp, Markus |
author_sort | Walter, Nike |
collection | PubMed |
description | Proximal femoral fractures are a serious complication, especially for elderly patients. Therefore, we have aimed to answer the following research question: What is the postfracture mortality rate in the elderly population and what are associated risk factors? For this, proximal femoral fractures that occurred between 1 January 2009 and 31 December 2019 were identified from the Medicare Physician Service Records database. The Kaplan–Meier (KM) method with the Fine and Gray subdistribution adaptation was used to determine rates of mortality. A semiparametric Cox regression model was applied, incorporating 23 measures as covariates to identify risk factors. The estimated 1 year mortality rate was 26.8% after head/neck fracture, 28.2% after intertrochanteric fracture, and 24.2% after subtrochanteric fracture. Male sex, age over 70 years, chronic obstructive pulmonary disease (COPD), cerebrovascular disease, chronic kidney disease, a concomitant fracture, congestive heart failure, diabetes mellitus, hypertension, insulin use, ischemic heart disease, morbid obesity, osteoporosis, tobacco dependence, and median household income were determined as risk factors for increased mortality. An early assessment of individual risk factors accessible for therapeutic treatment is crucial in the management of proximal femur fractures to aid in attempts at reducing the high mortality apparent in the elderly US population. |
format | Online Article Text |
id | pubmed-10293507 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-102935072023-06-28 Factors associated with mortality after proximal femoral fracture Walter, Nike Szymski, Dominik Kurtz, Steve Alt, Volker Lowenberg, David W. Lau, Edmund Rupp, Markus J Orthop Traumatol Brief Communication Proximal femoral fractures are a serious complication, especially for elderly patients. Therefore, we have aimed to answer the following research question: What is the postfracture mortality rate in the elderly population and what are associated risk factors? For this, proximal femoral fractures that occurred between 1 January 2009 and 31 December 2019 were identified from the Medicare Physician Service Records database. The Kaplan–Meier (KM) method with the Fine and Gray subdistribution adaptation was used to determine rates of mortality. A semiparametric Cox regression model was applied, incorporating 23 measures as covariates to identify risk factors. The estimated 1 year mortality rate was 26.8% after head/neck fracture, 28.2% after intertrochanteric fracture, and 24.2% after subtrochanteric fracture. Male sex, age over 70 years, chronic obstructive pulmonary disease (COPD), cerebrovascular disease, chronic kidney disease, a concomitant fracture, congestive heart failure, diabetes mellitus, hypertension, insulin use, ischemic heart disease, morbid obesity, osteoporosis, tobacco dependence, and median household income were determined as risk factors for increased mortality. An early assessment of individual risk factors accessible for therapeutic treatment is crucial in the management of proximal femur fractures to aid in attempts at reducing the high mortality apparent in the elderly US population. Springer International Publishing 2023-06-26 2023-12 /pmc/articles/PMC10293507/ /pubmed/37365418 http://dx.doi.org/10.1186/s10195-023-00715-5 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Brief Communication Walter, Nike Szymski, Dominik Kurtz, Steve Alt, Volker Lowenberg, David W. Lau, Edmund Rupp, Markus Factors associated with mortality after proximal femoral fracture |
title | Factors associated with mortality after proximal femoral fracture |
title_full | Factors associated with mortality after proximal femoral fracture |
title_fullStr | Factors associated with mortality after proximal femoral fracture |
title_full_unstemmed | Factors associated with mortality after proximal femoral fracture |
title_short | Factors associated with mortality after proximal femoral fracture |
title_sort | factors associated with mortality after proximal femoral fracture |
topic | Brief Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293507/ https://www.ncbi.nlm.nih.gov/pubmed/37365418 http://dx.doi.org/10.1186/s10195-023-00715-5 |
work_keys_str_mv | AT walternike factorsassociatedwithmortalityafterproximalfemoralfracture AT szymskidominik factorsassociatedwithmortalityafterproximalfemoralfracture AT kurtzsteve factorsassociatedwithmortalityafterproximalfemoralfracture AT altvolker factorsassociatedwithmortalityafterproximalfemoralfracture AT lowenbergdavidw factorsassociatedwithmortalityafterproximalfemoralfracture AT lauedmund factorsassociatedwithmortalityafterproximalfemoralfracture AT ruppmarkus factorsassociatedwithmortalityafterproximalfemoralfracture |