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Factors associated with mortality after proximal femoral fracture

Proximal femoral fractures are a serious complication, especially for elderly patients. Therefore, we have aimed to answer the following research question: What is the postfracture mortality rate in the elderly population and what are associated risk factors? For this, proximal femoral fractures tha...

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Autores principales: Walter, Nike, Szymski, Dominik, Kurtz, Steve, Alt, Volker, Lowenberg, David W., Lau, Edmund, Rupp, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293507/
https://www.ncbi.nlm.nih.gov/pubmed/37365418
http://dx.doi.org/10.1186/s10195-023-00715-5
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author Walter, Nike
Szymski, Dominik
Kurtz, Steve
Alt, Volker
Lowenberg, David W.
Lau, Edmund
Rupp, Markus
author_facet Walter, Nike
Szymski, Dominik
Kurtz, Steve
Alt, Volker
Lowenberg, David W.
Lau, Edmund
Rupp, Markus
author_sort Walter, Nike
collection PubMed
description Proximal femoral fractures are a serious complication, especially for elderly patients. Therefore, we have aimed to answer the following research question: What is the postfracture mortality rate in the elderly population and what are associated risk factors? For this, proximal femoral fractures that occurred between 1 January 2009 and 31 December 2019 were identified from the Medicare Physician Service Records database. The Kaplan–Meier (KM) method with the Fine and Gray subdistribution adaptation was used to determine rates of mortality. A semiparametric Cox regression model was applied, incorporating 23 measures as covariates to identify risk factors. The estimated 1 year mortality rate was 26.8% after head/neck fracture, 28.2% after intertrochanteric fracture, and 24.2% after subtrochanteric fracture. Male sex, age over 70 years, chronic obstructive pulmonary disease (COPD), cerebrovascular disease, chronic kidney disease, a concomitant fracture, congestive heart failure, diabetes mellitus, hypertension, insulin use, ischemic heart disease, morbid obesity, osteoporosis, tobacco dependence, and median household income were determined as risk factors for increased mortality. An early assessment of individual risk factors accessible for therapeutic treatment is crucial in the management of proximal femur fractures to aid in attempts at reducing the high mortality apparent in the elderly US population.
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spelling pubmed-102935072023-06-28 Factors associated with mortality after proximal femoral fracture Walter, Nike Szymski, Dominik Kurtz, Steve Alt, Volker Lowenberg, David W. Lau, Edmund Rupp, Markus J Orthop Traumatol Brief Communication Proximal femoral fractures are a serious complication, especially for elderly patients. Therefore, we have aimed to answer the following research question: What is the postfracture mortality rate in the elderly population and what are associated risk factors? For this, proximal femoral fractures that occurred between 1 January 2009 and 31 December 2019 were identified from the Medicare Physician Service Records database. The Kaplan–Meier (KM) method with the Fine and Gray subdistribution adaptation was used to determine rates of mortality. A semiparametric Cox regression model was applied, incorporating 23 measures as covariates to identify risk factors. The estimated 1 year mortality rate was 26.8% after head/neck fracture, 28.2% after intertrochanteric fracture, and 24.2% after subtrochanteric fracture. Male sex, age over 70 years, chronic obstructive pulmonary disease (COPD), cerebrovascular disease, chronic kidney disease, a concomitant fracture, congestive heart failure, diabetes mellitus, hypertension, insulin use, ischemic heart disease, morbid obesity, osteoporosis, tobacco dependence, and median household income were determined as risk factors for increased mortality. An early assessment of individual risk factors accessible for therapeutic treatment is crucial in the management of proximal femur fractures to aid in attempts at reducing the high mortality apparent in the elderly US population. Springer International Publishing 2023-06-26 2023-12 /pmc/articles/PMC10293507/ /pubmed/37365418 http://dx.doi.org/10.1186/s10195-023-00715-5 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Brief Communication
Walter, Nike
Szymski, Dominik
Kurtz, Steve
Alt, Volker
Lowenberg, David W.
Lau, Edmund
Rupp, Markus
Factors associated with mortality after proximal femoral fracture
title Factors associated with mortality after proximal femoral fracture
title_full Factors associated with mortality after proximal femoral fracture
title_fullStr Factors associated with mortality after proximal femoral fracture
title_full_unstemmed Factors associated with mortality after proximal femoral fracture
title_short Factors associated with mortality after proximal femoral fracture
title_sort factors associated with mortality after proximal femoral fracture
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293507/
https://www.ncbi.nlm.nih.gov/pubmed/37365418
http://dx.doi.org/10.1186/s10195-023-00715-5
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