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Gastric Xanthoma: A Rare Case Report

Xanthomas are characterized by the presence of foamy lipid-laden macrophages. The gastrointestinal tract is an uncommon site for xanthoma, with the stomach being the most favored location. They have been associated with various premalignant and malignant conditions of the stomach. We present a case...

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Detalles Bibliográficos
Autores principales: Kumari, Pummi, Sinha, Ruchi, Khanna, Nisha, Maji, Tanmoy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Society of Pathology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293599/
https://www.ncbi.nlm.nih.gov/pubmed/37383159
http://dx.doi.org/10.30699/ijp.2023.551854.2878
Descripción
Sumario:Xanthomas are characterized by the presence of foamy lipid-laden macrophages. The gastrointestinal tract is an uncommon site for xanthoma, with the stomach being the most favored location. They have been associated with various premalignant and malignant conditions of the stomach. We present a case of a 21-year-old female patient with dyspepsia of 4 months duration. Her lipid profile was mildly altered. On upper gastrointestinal endoscopy, multiple discrete yellow patches were found in the antrum, diagnosed as gastric xanthoma on microscopy. Various published literature has emphasized the frequent association of gastric xanthomas with gastritis, gastric atrophy, intestinal metaplasia, and gastric cancer. Hence, there is a necessity for early recognition, treatment of any coexistent pathology, and close clinical follow-up.