Single-cell transcriptomics reveals maturation of transplanted stem cell–derived retinal pigment epithelial cells toward native state

Transplantation of stem cell–derived retinal pigment epithelial (RPE) cells is considered a viable therapeutic option for age-related macular degeneration (AMD). Several landmark Phase I/II clinical trials have demonstrated safety and tolerability of RPE transplants in AMD patients, albeit with limi...

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Detalles Bibliográficos
Autores principales: Parikh, Bhav Harshad, Blakeley, Paul, Regha, Kakkad, Liu, Zengping, Yang, Binxia, Bhargava, Mayuri, Wong, Daniel Soo Lin, Tan, Queenie Shu Woon, Wong, Claudine See Wei, Wang, Hao Fei, Al-Mubaarak, Abdurrahmaan, Chou, Chai, Cheung, Chui Ming Gemmy, Lim, Kah Leong, Barathi, Veluchamy Amutha, Hunziker, Walter, Lingam, Gopal, Hu, Tim Xiaoming, Su, Xinyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293804/
https://www.ncbi.nlm.nih.gov/pubmed/37339216
http://dx.doi.org/10.1073/pnas.2214842120

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