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An Uncommon Presentation of Neonatal Lupus Erythematosus: A Case Report
Neonatal lupus erythematosus (NLE) is a rare autoimmune disorder of newborns and infants, born to usually asymptomatic mothers with lupus erythematosus. Clinical manifestations include variable cutaneous findings, with possible cardiac or hepatic involvement. We present a case of a 3-month-old baby...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294211/ https://www.ncbi.nlm.nih.gov/pubmed/37383322 http://dx.doi.org/10.1159/000530465 |
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author | Al Janahi, Sara Al Maashari, Raghda |
author_facet | Al Janahi, Sara Al Maashari, Raghda |
author_sort | Al Janahi, Sara |
collection | PubMed |
description | Neonatal lupus erythematosus (NLE) is a rare autoimmune disorder of newborns and infants, born to usually asymptomatic mothers with lupus erythematosus. Clinical manifestations include variable cutaneous findings, with possible cardiac or hepatic involvement. We present a case of a 3-month-old baby girl with NLE, born to an asymptomatic mother. Her atypical clinical presentation included hypopigmented atrophic scars on the temples. She improved with topical pimecrolimus cream, with almost complete resolution of the facial lesions and improvement in atrophy noted at the 4-month follow-up visit. Cutaneous findings of hypopigmentation and atrophic scarring are less commonly reported. To our knowledge, no similar cases have been published in the Middle East. We aim to share this interesting case, highlight the different clinical presentations of NLE and raise awareness among physicians about this variable phenotype of NLE for timely diagnosis of this uncommon entity. |
format | Online Article Text |
id | pubmed-10294211 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-102942112023-06-28 An Uncommon Presentation of Neonatal Lupus Erythematosus: A Case Report Al Janahi, Sara Al Maashari, Raghda Case Rep Dermatol Single Case Neonatal lupus erythematosus (NLE) is a rare autoimmune disorder of newborns and infants, born to usually asymptomatic mothers with lupus erythematosus. Clinical manifestations include variable cutaneous findings, with possible cardiac or hepatic involvement. We present a case of a 3-month-old baby girl with NLE, born to an asymptomatic mother. Her atypical clinical presentation included hypopigmented atrophic scars on the temples. She improved with topical pimecrolimus cream, with almost complete resolution of the facial lesions and improvement in atrophy noted at the 4-month follow-up visit. Cutaneous findings of hypopigmentation and atrophic scarring are less commonly reported. To our knowledge, no similar cases have been published in the Middle East. We aim to share this interesting case, highlight the different clinical presentations of NLE and raise awareness among physicians about this variable phenotype of NLE for timely diagnosis of this uncommon entity. S. Karger AG 2023-06-06 /pmc/articles/PMC10294211/ /pubmed/37383322 http://dx.doi.org/10.1159/000530465 Text en © 2023 The Author(s). Published by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission. |
spellingShingle | Single Case Al Janahi, Sara Al Maashari, Raghda An Uncommon Presentation of Neonatal Lupus Erythematosus: A Case Report |
title | An Uncommon Presentation of Neonatal Lupus Erythematosus: A Case Report |
title_full | An Uncommon Presentation of Neonatal Lupus Erythematosus: A Case Report |
title_fullStr | An Uncommon Presentation of Neonatal Lupus Erythematosus: A Case Report |
title_full_unstemmed | An Uncommon Presentation of Neonatal Lupus Erythematosus: A Case Report |
title_short | An Uncommon Presentation of Neonatal Lupus Erythematosus: A Case Report |
title_sort | uncommon presentation of neonatal lupus erythematosus: a case report |
topic | Single Case |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294211/ https://www.ncbi.nlm.nih.gov/pubmed/37383322 http://dx.doi.org/10.1159/000530465 |
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