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Computational drug repositioning for the identification of new agents to sensitize drug-resistant breast tumors across treatments and receptor subtypes

INTRODUCTION: Drug resistance is a major obstacle in cancer treatment and can involve a variety of different factors. Identifying effective therapies for drug resistant tumors is integral for improving patient outcomes. METHODS: In this study, we applied a computational drug repositioning approach t...

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Detalles Bibliográficos
Autores principales: Yu, Katharine, Basu, Amrita, Yau, Christina, Wolf, Denise M., Goodarzi, Hani, Bandyopadhyay, Sourav, Korkola, James E., Hirst, Gillian L., Asare, Smita, DeMichele, Angela, Hylton, Nola, Yee, Douglas, Esserman, Laura, van ‘t Veer, Laura, Sirota, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294228/
https://www.ncbi.nlm.nih.gov/pubmed/37384294
http://dx.doi.org/10.3389/fonc.2023.1192208