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Pharmacologic inhibition of IL11/STAT3 signaling increases MHC-I expression and T cell infiltration

BACKGROUND: Recent studies have discovered an emerging role of IL11 in various colitis-associated cancers, suggesting that IL11 mainly promotes tumor cell survival and proliferation in regulating tumorigenesis. Herein we aimed to reveal a novel function of IL-11 through STAT3 signaling in regulating...

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Detalles Bibliográficos
Autores principales:	Xiong, Wenjun, Chen, Yuehong, Zhang, Chaoting, Li, Jin, Huang, Haipeng, Zhu, Yu, Deng, Guangxu, Cheng, Junhong, Lin, Yixiong, Shi, Zhimin, Mou, Tingyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294373/ https://www.ncbi.nlm.nih.gov/pubmed/37365574 http://dx.doi.org/10.1186/s12967-023-04079-6

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