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GABAergic neurons differentiated from BDNF- and Dlx2-modified neural stem cells restore disrupted neural circuits in brainstem stroke

BACKGROUND: Brainstem stroke causes severe and persistent neurological impairment. Due to the limited spontaneous recovery and regeneration of the disrupted neural circuits, transplantation of exogenous neural stem cells (NSCs) was an alternative, while there were limitations for primitive NSCs. MET...

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Detalles Bibliográficos
Autores principales: Tang, Xiangyue, Wu, Li, Zhu, Juehua, Xu, Mindong, Li, Shaojun, Zeng, Guanfeng, Zhu, Shuanggen, Jiang, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294474/
https://www.ncbi.nlm.nih.gov/pubmed/37365654
http://dx.doi.org/10.1186/s13287-023-03378-5