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GABAergic neurons differentiated from BDNF- and Dlx2-modified neural stem cells restore disrupted neural circuits in brainstem stroke
BACKGROUND: Brainstem stroke causes severe and persistent neurological impairment. Due to the limited spontaneous recovery and regeneration of the disrupted neural circuits, transplantation of exogenous neural stem cells (NSCs) was an alternative, while there were limitations for primitive NSCs. MET...
Autores principales: | Tang, Xiangyue, Wu, Li, Zhu, Juehua, Xu, Mindong, Li, Shaojun, Zeng, Guanfeng, Zhu, Shuanggen, Jiang, Yongjun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294474/ https://www.ncbi.nlm.nih.gov/pubmed/37365654 http://dx.doi.org/10.1186/s13287-023-03378-5 |
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