Human papillomavirus integration transforms chromatin to drive oncogenesis

BACKGROUND: Human papillomavirus (HPV) drives almost all cervical cancers and up to 70% of head and neck cancers. Frequent integration into the host genome occurs predominantly in tumorigenic types of HPV. We hypothesize that changes in chromatin state at the location of integration can result in ch...

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Detalles Bibliográficos
Autores principales: Karimzadeh, Mehran, Arlidge, Christopher, Rostami, Ariana, Lupien, Mathieu, Bratman, Scott V., Hoffman, Michael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294493/
https://www.ncbi.nlm.nih.gov/pubmed/37365652
http://dx.doi.org/10.1186/s13059-023-02926-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294493/
https://www.ncbi.nlm.nih.gov/pubmed/37365652
http://dx.doi.org/10.1186/s13059-023-02926-9

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