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Trastuzumab-resistant breast cancer cells-derived tumor xenograft models exhibit distinct sensitivity to lapatinib treatment in vivo

BACKGROUND: Resistance to HER2-targeted therapies, including the monoclonal antibody trastuzumab and tyrosine kinase inhibitor lapatinib, frequently occurs and currently represents a significant clinical challenge in the management of HER2-positive breast cancer. We previously showed that the trastu...

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Detalles Bibliográficos
Autores principales:	Liu, Hao, Ruan, Sanbao, Larsen, Margaret E., Tan, Congcong, Liu, Bolin, Lyu, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294508/ https://www.ncbi.nlm.nih.gov/pubmed/37370010 http://dx.doi.org/10.1186/s12575-023-00212-3

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