Aberrant palmitoylation caused by a ZDHHC21 mutation contributes to pathophysiology of Alzheimer’s disease

BACKGROUND: The identification of pathogenic mutations in Alzheimer’s disease (AD) causal genes led to a better understanding of the pathobiology of AD. Familial Alzheimer’s disease (FAD) is known to be associated with mutations in the APP, PSEN1, and PSEN2 genes involved in Aβ production; however,...

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Detalles Bibliográficos
Autores principales: Li, Wenwen, Pang, Yana, Wang, Yan, Mei, Fan, Guo, Mengmeng, Wei, Yiping, Li, Xinyue, Qin, Wei, Wang, Wei, Jia, Longfei, Jia, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294511/
https://www.ncbi.nlm.nih.gov/pubmed/37365538
http://dx.doi.org/10.1186/s12916-023-02930-7

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