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Design, synthesis, and biological evaluation of morpholinopyrimidine derivatives as anti-inflammatory agents

Here, we outline the synthesis of a few 2-methoxy-6-((4-(6-morpholinopyrimidin-4-yl)piperazin-1-yl)(phenyl)methyl)phenol derivatives and assess their anti-inflammatory activity in macrophage cells that have been stimulated by LPS. Among these newly synthesized morpholinopyrimidine derivatives, 2-met...

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Detalles Bibliográficos
Autores principales: Fatima, Sadaf, Zaki, Almaz, Madhav, Hari, Khatoon, Bibi Shaguftah, Rahman, Abdur, Manhas, Mohd Wasif, Hoda, Nasimul, Ali, Syed Mansoor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294549/
https://www.ncbi.nlm.nih.gov/pubmed/37383684
http://dx.doi.org/10.1039/d3ra01893h