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Hyperphosphorylation of the Group A Streptococcal Control of Virulence Regulator Increases Promoter Occupancy Specifically at Virulence Factor-Encoding Genes

The control of virulence two-component gene regulatory system (CovRS) is critical to the pathogenesis of many medically important streptococci. In emm1 group A streptococci (GAS), CovR directly binds the promoters of numerous GAS virulence factor-encoding genes. Elimination of CovS phosphatase activ...

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Detalles Bibliográficos
Autores principales:	Horstmann, Nicola, Tran, Chau Nguyen, Flores, Anthony R., Shelburne, Samuel A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294628/ https://www.ncbi.nlm.nih.gov/pubmed/37289078 http://dx.doi.org/10.1128/jb.00118-23

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