Bacterial TLR2/6 Ligands Block Ciliogenesis, Derepress Hedgehog Signaling, and Expand the Neocortex

Microbial components have a range of direct effects on the fetal brain. However, little is known about the cellular targets and molecular mechanisms that mediate these effects. Neural progenitor cells (NPCs) control the size and architecture of the brain and understanding the mechanisms regulating N...

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Detalles Bibliográficos
Autores principales: Mann, Beth, Crawford, Jeremy Chase, Reddy, Kavya, Lott, Josi, Youn, Yong Ha, Gao, Geli, Guy, Cliff, Chou, Ching-Heng, Darnell, Daniel, Trivedi, Sanchit, Bomme, Perrine, Loughran, Allister J., Thomas, Paul G., Han, Young-Goo, Tuomanen, Elaine I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294647/
https://www.ncbi.nlm.nih.gov/pubmed/37052506
http://dx.doi.org/10.1128/mbio.00510-23

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