Apobec3A Deamination Functions Are Involved in Antagonizing Efficient Human Adenovirus Replication and Gene Expression

Apobec3A is involved in the antiviral host defense, targeting nuclear DNA, introducing point mutations, and thereby activating DNA damage response (DDR). Here, we found a significant upregulation of Apobec3A during HAdV infection, including Apobec3A protein stabilization mediated by the viral protei...

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Detalles Bibliográficos
Autores principales: Göttig, Lilian, Weiß, Christina, Stubbe, Miona, Hanrieder, Lisa, Hofmann, Samuel, Grodziecki, Alessandro, Stadler, Daniela, Carpentier, Arnaud, Protzer, Ulrike, Schreiner, Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294656/
https://www.ncbi.nlm.nih.gov/pubmed/37154747
http://dx.doi.org/10.1128/mbio.03478-22

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