Aging-Associated Augmentation of Gut Microbiome Virulence Capability Drives Sepsis Severity

Prior research has focused on host factors as mediators of exaggerated sepsis-associated morbidity and mortality in older adults. This focus on the host, however, has failed to identify therapies that improve sepsis outcomes in the elderly. We hypothesized that the increased susceptibility of the ag...

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Detalles Bibliográficos
Autores principales: Colbert, James F., Kirsch, Joshua M., Erzen, Christopher L., Langouët-Astrié, Christophe J., Thompson, Grace E., McMurtry, Sarah A., Kofonow, Jennifer M., Robertson, Charles E., Kovacs, Elizabeth J., Sullivan, Ryan C., Hippensteel, Joseph A., Sawant, Namrata V., De Nisco, Nicole J., McCollister, Bruce D., Schwartz, Robert S., Horswill, Alexander R., Frank, Daniel N., Duerkop, Breck A., Schmidt, Eric P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294665/
https://www.ncbi.nlm.nih.gov/pubmed/37102874
http://dx.doi.org/10.1128/mbio.00052-23

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