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Engineered Superinfective Pf Phage Prevents Dissemination of Pseudomonas aeruginosa in a Mouse Burn Model

Pf is a filamentous bacteriophage integrated in the chromosome of most clinical isolates of Pseudomonas aeruginosa. Under stress conditions, mutations occurring in the Pf genome result in the emergence of superinfective variants of Pf (SI-Pf) that are capable of circumventing phage immunity; therefo...

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Detalles Bibliográficos
Autores principales:	Prokopczuk, Federico I., Im, Hansol, Campos-Gomez, Javier, Orihuela, Carlos J., Martínez, Eriel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2023
Materias:	Observation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294672/ https://www.ncbi.nlm.nih.gov/pubmed/37039641 http://dx.doi.org/10.1128/mbio.00472-23

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