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Single-cell RNA-seq uncovers dynamic processes orchestrated by RNA-binding protein DDX43 in chromatin remodeling during spermiogenesis
Mammalian spermatogenesis shows prominent chromatin and transcriptomic switches in germ cells, but it is unclear how such dynamics are controlled. Here we identify RNA helicase DDX43 as an essential regulator of the chromatin remodeling process during spermiogenesis. Testis-specific Ddx43 knockout m...
Główni autorzy: | , , , , , , , , , , , , |
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Format: | Online Artykuł Texto |
Język: | English |
Wydane: |
Nature Publishing Group UK
2023
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Hasła przedmiotowe: | |
Dostęp online: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294715/ https://www.ncbi.nlm.nih.gov/pubmed/37120627 http://dx.doi.org/10.1038/s41467-023-38199-w |