Single-cell RNA-seq uncovers dynamic processes orchestrated by RNA-binding protein DDX43 in chromatin remodeling during spermiogenesis

Mammalian spermatogenesis shows prominent chromatin and transcriptomic switches in germ cells, but it is unclear how such dynamics are controlled. Here we identify RNA helicase DDX43 as an essential regulator of the chromatin remodeling process during spermiogenesis. Testis-specific Ddx43 knockout m...

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Detalhes bibliográficos
Autores principales: Tan, Huanhuan, Wang, Weixu, Zhou, Congjin, Wang, Yanfeng, Zhang, Shu, Yang, Pinglan, Guo, Rui, Chen, Wei, Zhang, Jinwen, Ye, Lan, Cui, Yiqiang, Ni, Ting, Zheng, Ke
Formato: Online Artigo Texto
Idioma:English
Publicado em: Nature Publishing Group UK 2023
Assuntos:
Article
Acesso em linha:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294715/
https://www.ncbi.nlm.nih.gov/pubmed/37120627
http://dx.doi.org/10.1038/s41467-023-38199-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294715/
https://www.ncbi.nlm.nih.gov/pubmed/37120627
http://dx.doi.org/10.1038/s41467-023-38199-w

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