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Key Factors Regulating the Interdomain Dynamics May Contribute to the Assembly of ASC

SIMPLE SUMMARY: The innate immune system in our bodies responds to pathogenic infections and cellular damage by inducing pyroptosis through the assembly of inflammasome complexes. The apoptosis-associated speck-like protein containing a CARD (ASC) serves as an adapter, recognizing pattern recognitio...

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Detalles Bibliográficos
Autores principales: Li, Tongtong, Gil Pineda, Laura I., Stevens, Amy O., He, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294833/
https://www.ncbi.nlm.nih.gov/pubmed/37372082
http://dx.doi.org/10.3390/biology12060796