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Induction of Reactive Bone Stromal Fibroblasts in 3D Models of Prostate Cancer Bone Metastases

SIMPLE SUMMARY: When prostate cancer cells spread to other parts of the body (metastasise), they frequently migrate to the bone. Here they encounter a microenvironment that differs greatly from that in the primary tumour (prostate), namely interactions with bone-specific cells, including fibroblasts...

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Detalles Bibliográficos
Autores principales: Windus, Louisa C. E., Matigian, Nicholas, Avery, Vicky M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294842/
https://www.ncbi.nlm.nih.gov/pubmed/37372146
http://dx.doi.org/10.3390/biology12060861