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Antimicrobial Properties and Mode of Action of Cryptdin-4, a Mouse α-Defensin Regulated by Peptide Redox Structures and Bacterial Cultivation Conditions

Cryptdin-4 (crp4) is an enteric α-defensin derived from mice, and is a main mediator of immunity to oral infections and a determinant of the composition of the intestinal microbiota. Structurally, crp4 exists in two states: the oxidized form (crp4oxi), constrained by three invariant disulfide bonds,...

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Detalles Bibliográficos
Autores principales:	Wang, Yi, Song, Yuchi, Yan, Shaonan, Hiramine, Rina, Ohnishi, Yuki, Yokoi, Yuki, Nakamura, Kiminori, Kikukawa, Takashi, Ayabe, Tokiyoshi, Aizawa, Tomoyasu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295000/ https://www.ncbi.nlm.nih.gov/pubmed/37370366 http://dx.doi.org/10.3390/antibiotics12061047

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