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Optimization and characterization of miRNA-129-5p-encapsulated poly (lactic-co-glycolic acid) nanoparticles to reprogram activated microglia

Microglia have become a therapeutic target of many inflammation-mediated diseases in the central nervous system (CNS). Recently, microRNA (miRNA) has been proposed as an important regulator of immune responses. Specifically, miRNA-129-5p has been shown to play critical roles in the regulation of mic...

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Detalles Bibliográficos
Autores principales: Kalashnikova, Irina, Cambell, Heather, Kolpek, Daniel, Park, Jonghyuck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295030/
https://www.ncbi.nlm.nih.gov/pubmed/37383067
http://dx.doi.org/10.1039/d3na00149k