Cargando…

Bilirubin-Induced Transcriptomic Imprinting in Neonatal Hyperbilirubinemia

SIMPLE SUMMARY: Severe neonatal hyperbilirubinemia may damage the brain, leading to motor, cognitive, and auditory abnormalities. We recently discovered that bilirubin might act by controlling the genetic developmental program of the cerebellum, a region of the brain well known to be susceptible to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Llido, John Paul, Fioriti, Emanuela, Pascut, Devis, Giuffrè, Mauro, Bottin, Cristina, Zanconati, Fabrizio, Tiribelli, Claudio, Gazzin, Silvia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295065/ https://www.ncbi.nlm.nih.gov/pubmed/37372119 http://dx.doi.org/10.3390/biology12060834

Ejemplares similares

Evaluation of region selective bilirubin-induced brain damage as a basis for a pharmacological treatment
por: Dal Ben, Matteo, et al.
Publicado: (2017)

Neonatal hyperbilirubinemia
por: Ben, Matteo Dal, et al.
Publicado: (2014)

Histone acetylation as a new mechanism for bilirubin-induced encephalopathy in the Gunn rat
por: Vianello, Eleonora, et al.
Publicado: (2018)

Bilirubin and Redox Stress in Age-Related Brain Diseases
por: Llido, John Paul, et al.
Publicado: (2023)

Celiac Disease and Neurological Manifestations: From Gluten to Neuroinflammation
por: Giuffrè, Mauro, et al.
Publicado: (2022)

Inflammation, Dopaminergic Brain and Bilirubin
por: Jayanti, Sri, et al.
Publicado: (2023)

Life-Long Hyperbilirubinemia Exposure and Bilirubin Priming Prevent In Vitro Metabolic Damage
por: Bianco, Annalisa, et al.
Publicado: (2021)

Bilirubin: A Promising Therapy for Parkinson’s Disease
por: Jayanti, Sri, et al.
Publicado: (2021)

The Role of Bilirubin and the Other “Yellow Players” in Neurodegenerative Diseases
por: Jayanti, Sri, et al.
Publicado: (2020)

Bilirubin Prevents the TH(+) Dopaminergic Neuron Loss in a Parkinson’s Disease Model by Acting on TNF-α
por: Jayanti, Sri, et al.
Publicado: (2022)

Weighted miRNA co-expression networks analysis identifies circulating miRNA predicting overall survival in hepatocellular carcinoma patients
por: Pascut, Devis, et al.
Publicado: (2020)

Bilirubin-Induced Oxidative Stress Leads to DNA Damage in the Cerebellum of Hyperbilirubinemic Neonatal Mice and Activates DNA Double-Strand Break Repair Pathways in Human Cells
por: Rawat, Vipin, et al.
Publicado: (2018)

Transcutaneous bilirubin level to predict hyperbilirubinemia in preterm neonates
por: Rahmawati, Dewi, et al.
Publicado: (2020)

Transport and Metabolism at Blood–Brain Interfaces and in Neural Cells: Relevance to Bilirubin-Induced Encephalopathy
por: Gazzin, Silvia, et al.
Publicado: (2012)

Homocysteine in Neurology: A Possible Contributing Factor to Small Vessel Disease
por: Moretti, Rita, et al.
Publicado: (2021)

Earliest Mechanisms of Dopaminergic Neurons Sufferance in a Novel Slow Progressing Ex Vivo Model of Parkinson Disease in Rat Organotypic Cultures of Substantia Nigra
por: Dal Ben, Matteo, et al.
Publicado: (2019)

Nonalcoholic Fatty Liver Disease and Altered Neuropsychological Functions in Patients with Subcortical Vascular Dementia
por: Moretti, Rita, et al.
Publicado: (2022)

Silencing efficacy prediction: a retrospective study on target mRNA features
por: Pascut, Devis, et al.
Publicado: (2015)

The Biological Effects of Bilirubin Photoisomers
por: Jasprova, Jana, et al.
Publicado: (2016)

HCC occurrence after DAA treatments: molecular tools to assess the post-treatment risk and surveillance
por: Pascut, Devis, et al.
Publicado: (2020)

Repeated double cross-validation applied to the PCA-LDA classification of SERS spectra: a case study with serum samples from hepatocellular carcinoma patients
por: Gurian, Elisa, et al.
Publicado: (2020)

Umbilical cord blood bilirubins, gestational age, and maternal race predict neonatal hyperbilirubinemia
por: Castillo, Adrian, et al.
Publicado: (2018)

Clinical Assessment of Neuroinflammatory Markers and Antioxidants in Neonates with Hyperbilirubinemia and Their Association with Acute Bilirubin Encephalopathy
por: Midan, Dina Abdel Razek, et al.
Publicado: (2022)

Cord blood bilirubin and prediction of neonatal hyperbilirubinemia and perinatal infection in newborns at risk of hemolysis()
por: Kardum, Darjan, et al.
Publicado: (2020)

Bilirubin 2022: The Past, the Present and the Future
por: Bellarosa, Cristina, et al.
Publicado: (2022)

Crosslinked Bifunctional Particles for the Removal of Bilirubin in Hyperbilirubinemia Cases
por: Garrido, María del Prado, et al.
Publicado: (2023)

Multiple Genetic Modifiers of Bilirubin Metabolism Involvement in Significant Neonatal Hyperbilirubinemia in Patients of Chinese Descent
por: Yang, Hui, et al.
Publicado: (2015)

Incidence and risk factors of acute bilirubin encephalopathy in neonates with hyperbilirubinemia presenting at secondary care hospital
por: Rauf, Saba, et al.
Publicado: (2023)

Selection and validation of miR-1280 as a suitable endogenous normalizer for qRT-PCR Analysis of serum microRNA expression in Hepatocellular Carcinoma
por: Pratama, Muhammad Yogi, et al.
Publicado: (2020)

The Role of microRNAs in the Cisplatin- and Radio-Resistance of Cervical Cancer
por: Masadah, Rina, et al.
Publicado: (2021)

Early predictive value of cord blood bilirubin and dynamic monitoring of transcutaneous bilirubin for hyperbilirubinemia of newborns
por: Guan, Haishan, et al.
Publicado: (2017)

A Hypothesis for Using Pathway Genetic Load Analysis for Understanding Complex Outcomes in Bilirubin Encephalopathy
por: Riordan, Sean M., et al.
Publicado: (2016)

Effect of Low versus Moderate Dose of Clofibrate on Serum Bilirubin in Healthy Term Neonates with Indirect Hyperbilirubinemia
por: Eghbalian, Fatemeh, et al.
Publicado: (2013)

Nomogram for Acute Bilirubin Encephalopathy Risk in Newborns With Extreme Hyperbilirubinemia
por: Qu, Yangming, et al.
Publicado: (2020)

Curcumin Prevents Cerebellar Hypoplasia and Restores the Behavior in Hyperbilirubinemic Gunn Rat by a Pleiotropic Effect on the Molecular Effectors of Brain Damage
por: Gazzin, Silvia, et al.
Publicado: (2020)

Neuro-inflammatory effects of photodegradative products of bilirubin
por: Jašprová, J., et al.
Publicado: (2018)

Circulatory miRNA as a Biomarker for Therapy Response and Disease-Free Survival in Hepatocellular Carcinoma
por: Pratama, Muhammad Yogi, et al.
Publicado: (2020)

The Crosstalk between Tumor Cells and the Microenvironment in Hepatocellular Carcinoma: The Role of Exosomal microRNAs and Their Clinical Implications
por: Pascut, Devis, et al.
Publicado: (2020)

Circulating Long and Circular Noncoding RNA as Non-Invasive Diagnostic Tools of Hepatocellular Carcinoma
por: Sukowati, Caecilia H. C., et al.
Publicado: (2021)

Modulation of Mrp1 (ABCc1) and Pgp (ABCb1) by Bilirubin at the Blood-CSF and Blood-Brain Barriers in the Gunn Rat
por: Gazzin, Silvia, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_4hfqq5o94gs591uj587g2tc8cd