A Rat Model of the Brain-Derived Neurotrophic Factor Val66Met Polymorphism Shows Attenuated Motivation for Alcohol Self-Administration and Diminished Propensity for Cue-Induced Relapse in Females

SIMPLE SUMMARY: The growth factor brain-derived neurotrophic factor (BDNF) has been implicated in alcohol use disorder. Val66Met is a common variant of the BDNF gene which reduces BDNF release in the brain. Val66Met has been suggested as a risk factor for psychiatric disorders and substance use. Usi...

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Detalles Bibliográficos
Autores principales: Jaehne, Emily J., McInerney, Elizabeth, Sharma, Ronan, Genders, Shannyn G., Djouma, Elvan, van den Buuse, Maarten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295107/
https://www.ncbi.nlm.nih.gov/pubmed/37372084
http://dx.doi.org/10.3390/biology12060799

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