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PD-1(+) IFN-γ(+) subset of CD8(+) T cell in circulation predicts response to anti–PD-1 therapy in NSCLC

BACKGROUND: Treatment with programmed cell death protein-1 (PD-1) antibodies has minimal response rates in patients with non–small cell lung cancer (NSCLC), and, actually, they are treated with chemotherapy combined with anti–PD-1 therapy clinically. Reliable markers based on circulating immune cell...

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Detalles Bibliográficos
Autores principales: Chen, Wenxiu, Hua, Yiting, Shan, Conghui, Wei, Jia, Zhou, Yutong, Pan, Shiyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295133/
https://www.ncbi.nlm.nih.gov/pubmed/37384302
http://dx.doi.org/10.3389/fonc.2023.1182301