Small extracellular vesicles derived from human adipose‐derived mesenchymal stromal cells cultured in a new chemically‐defined contaminate‐free media exhibit enhanced biological and therapeutic effects on human chondrocytes in vitro and in a mouse osteoarthritis model

Human small extracellular vesicles (sEVs) derived from adipose‐derived mesenchymal stromal cells (ASC) have been reported to suppress the progression of osteoarthritis (OA) in animal studies and subsequently, translation of this potential to assess their clinical efficacy is anticipated. However, fa...

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Detalles Bibliográficos
Autores principales: Hanai, Hiroto, Hart, David A., Jacob, George, Shimomura, Kazunori, Ando, Wataru, Yoshioka, Yusuke, Ochiya, Takahiro, Nakagawa, Shinicihi, Nakamura, Masato, Okada, Seiji, Nakamura, Norimasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Technical Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295161/
https://www.ncbi.nlm.nih.gov/pubmed/37367299
http://dx.doi.org/10.1002/jev2.12337

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