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CDC6 as a Key Inhibitory Regulator of CDK1 Activation Dynamics and the Timing of Mitotic Entry and Progression

SIMPLE SUMMARY: The kinetics of Cyclin Dependent Kinase 1 (CDK1) activation must be strictly controlled to guarantee a timely and physiological entry into mitosis. CDC6, a known S-phase regulator, has recently been found as a critical component in mitotic CDK1 activation cascade in early embryonic d...

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Detalles Bibliográficos
Autores principales:	El Dika, Mohammed, Dudka, Damian, Kloc, Malgorzata, Kubiak, Jacek Z.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295169/ https://www.ncbi.nlm.nih.gov/pubmed/37372141 http://dx.doi.org/10.3390/biology12060855

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