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A Unique Response Behavior in the Dissolved Oxygen Tension in E. coli Minibioreactor Cultivations with Intermittent Feeding

Intermittent bolus feeding for E. coli cultivations in minibioreactor systems (MBRs) profoundly affects the cell metabolism. Bolus feeding leads to temporal substrate surplus and transient oxygen limitation, which triggers the formation of inhibitory byproducts. Due to the high oxygen demand right a...

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Detalles Bibliográficos
Autores principales: Jouned, M. Adnan, Kager, Julian, Rajamanickam, Vignesh, Herwig, Christoph, Barz, Tilman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295202/
https://www.ncbi.nlm.nih.gov/pubmed/37370611
http://dx.doi.org/10.3390/bioengineering10060681

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