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Contribution of Physical Activity to the Oxidative and Antioxidant Potential in 60–65-Year-Old Seniors
Both acute exercise and regular physical activity (PA) are directly related to the redox system. However, at present, there are data suggesting both positive and negative relationships between the PA and oxidation. In addition, there is a limited number of publications differentiating the relationsh...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295210/ https://www.ncbi.nlm.nih.gov/pubmed/37371930 http://dx.doi.org/10.3390/antiox12061200 |
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author | Sołtysik, Bartłomiej K. Karolczak, Kamil Kostka, Tomasz Stephenson, Serena S. Watala, Cezary Kostka, Joanna |
author_facet | Sołtysik, Bartłomiej K. Karolczak, Kamil Kostka, Tomasz Stephenson, Serena S. Watala, Cezary Kostka, Joanna |
author_sort | Sołtysik, Bartłomiej K. |
collection | PubMed |
description | Both acute exercise and regular physical activity (PA) are directly related to the redox system. However, at present, there are data suggesting both positive and negative relationships between the PA and oxidation. In addition, there is a limited number of publications differentiating the relationships between PA and numerous markers of plasma and platelets targets for the oxidative stress. In this study, in a population of 300 participants from central Poland (covering the age range between 60 and 65 years), PA was assessed as regards energy expenditure (PA-EE) and health-related behaviors (PA-HRB). Total antioxidant potential (TAS), total oxidative stress (TOS) and several other markers of an oxidative stress, monitored in platelet and plasma lipids and proteins, were then determined. The association of PA with oxidative stress was determined taking into the account basic confounders, such as age, sex and the set of the relevant cardiometabolic factors. In simple correlations, platelet lipid peroxides, free thiol and amino groups of platelet proteins, as well as the generation of superoxide anion radical, were inversely related with PA-EE. In multivariate analyses, apart from other cardiometabolic factors, a significant positive impact of PA-HRB was revealed for TOS (inverse relationship), while in the case of PA-EE, the effect was found to be positive (inverse association) for lipid peroxides and superoxide anion but negative (lower concentration) for free thiol and free amino groups in platelets proteins. Therefore, the impact of PA may be different on oxidative stress markers in platelets as compared to plasma proteins and also dissimilar on platelet lipids and proteins. These associations are more visible for platelets than plasma markers. For lipid oxidation, PA seems to have protective effect. In the case of platelets proteins, PA tends to act as pro-oxidative factor. |
format | Online Article Text |
id | pubmed-10295210 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-102952102023-06-28 Contribution of Physical Activity to the Oxidative and Antioxidant Potential in 60–65-Year-Old Seniors Sołtysik, Bartłomiej K. Karolczak, Kamil Kostka, Tomasz Stephenson, Serena S. Watala, Cezary Kostka, Joanna Antioxidants (Basel) Article Both acute exercise and regular physical activity (PA) are directly related to the redox system. However, at present, there are data suggesting both positive and negative relationships between the PA and oxidation. In addition, there is a limited number of publications differentiating the relationships between PA and numerous markers of plasma and platelets targets for the oxidative stress. In this study, in a population of 300 participants from central Poland (covering the age range between 60 and 65 years), PA was assessed as regards energy expenditure (PA-EE) and health-related behaviors (PA-HRB). Total antioxidant potential (TAS), total oxidative stress (TOS) and several other markers of an oxidative stress, monitored in platelet and plasma lipids and proteins, were then determined. The association of PA with oxidative stress was determined taking into the account basic confounders, such as age, sex and the set of the relevant cardiometabolic factors. In simple correlations, platelet lipid peroxides, free thiol and amino groups of platelet proteins, as well as the generation of superoxide anion radical, were inversely related with PA-EE. In multivariate analyses, apart from other cardiometabolic factors, a significant positive impact of PA-HRB was revealed for TOS (inverse relationship), while in the case of PA-EE, the effect was found to be positive (inverse association) for lipid peroxides and superoxide anion but negative (lower concentration) for free thiol and free amino groups in platelets proteins. Therefore, the impact of PA may be different on oxidative stress markers in platelets as compared to plasma proteins and also dissimilar on platelet lipids and proteins. These associations are more visible for platelets than plasma markers. For lipid oxidation, PA seems to have protective effect. In the case of platelets proteins, PA tends to act as pro-oxidative factor. MDPI 2023-05-31 /pmc/articles/PMC10295210/ /pubmed/37371930 http://dx.doi.org/10.3390/antiox12061200 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Sołtysik, Bartłomiej K. Karolczak, Kamil Kostka, Tomasz Stephenson, Serena S. Watala, Cezary Kostka, Joanna Contribution of Physical Activity to the Oxidative and Antioxidant Potential in 60–65-Year-Old Seniors |
title | Contribution of Physical Activity to the Oxidative and Antioxidant Potential in 60–65-Year-Old Seniors |
title_full | Contribution of Physical Activity to the Oxidative and Antioxidant Potential in 60–65-Year-Old Seniors |
title_fullStr | Contribution of Physical Activity to the Oxidative and Antioxidant Potential in 60–65-Year-Old Seniors |
title_full_unstemmed | Contribution of Physical Activity to the Oxidative and Antioxidant Potential in 60–65-Year-Old Seniors |
title_short | Contribution of Physical Activity to the Oxidative and Antioxidant Potential in 60–65-Year-Old Seniors |
title_sort | contribution of physical activity to the oxidative and antioxidant potential in 60–65-year-old seniors |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295210/ https://www.ncbi.nlm.nih.gov/pubmed/37371930 http://dx.doi.org/10.3390/antiox12061200 |
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