Cargando…

Selective Inhibition of Soluble Tumor Necrosis Factor Alters the Neuroinflammatory Response following Moderate Spinal Cord Injury in Mice

SIMPLE SUMMARY: Blocking detrimental neuroinflammation and boosting a pro-regenerative environment are promising new therapeutic approaches in spinal cord injury (SCI). Selective blocking of the soluble (sol) form of the cytokine tumor necrosis factor (TNF) while maintaining the membrane-bound form...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lund, Minna Christiansen, Ellman, Ditte Gry, Nielsen, Pernille Vinther, Raffaele, Stefano, Fumagalli, Marta, Guzman, Raphael, Degn, Matilda, Brambilla, Roberta, Meyer, Morten, Clausen, Bettina Hjelm, Lambertsen, Kate Lykke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295415/ https://www.ncbi.nlm.nih.gov/pubmed/37372129 http://dx.doi.org/10.3390/biology12060845

Ejemplares similares

The Inflammatory Response after Moderate Contusion Spinal Cord Injury: A Time Study
por: Lund, Minna Christiansen, et al.
Publicado: (2022)

Genetic Ablation of Soluble TNF Does Not Affect Lesion Size and Functional Recovery after Moderate Spinal Cord Injury in Mice
por: Ellman, Ditte Gry, et al.
Publicado: (2016)

Topical Administration of a Soluble TNF Inhibitor Reduces Infarct Volume After Focal Cerebral Ischemia in Mice
por: Yli-Karjanmaa, Minna, et al.
Publicado: (2019)

Bone Marrow-Derived IL-1Ra Increases TNF Levels Poststroke
por: von Linstow, Christian Ulrich, et al.
Publicado: (2021)

Conditional Ablation of Myeloid TNF Improves Functional Outcome and Decreases Lesion Size after Spinal Cord Injury in Mice
por: Ellman, Ditte Gry, et al.
Publicado: (2020)

The loss-of-function disease-mutation G301R in the Na(+)/K(+)-ATPase α(2) isoform decreases lesion volume and improves functional outcome after acute spinal cord injury in mice
por: Ellman, Ditte Gry, et al.
Publicado: (2017)

Post-stroke inflammation—target or tool for therapy?
por: Lambertsen, Kate Lykke, et al.
Publicado: (2018)

USP25 Inhibits Neuroinflammatory Responses After Cerebral Ischemic Stroke by Deubiquitinating TAB2
por: Li, Zhongding, et al.
Publicado: (2023)

Conditional ablation of myeloid TNF increases lesion volume after experimental stroke in mice, possibly via altered ERK1/2 signaling
por: Clausen, Bettina Hjelm, et al.
Publicado: (2016)

Inflammation leads to distinct populations of extracellular vesicles from microglia
por: Yang, Yiyi, et al.
Publicado: (2018)

Interleukin-1 Mediates Ischemic Brain Injury via Induction of IL-17A in γδ T Cells and CXCL1 in Astrocytes
por: Schädlich, Ines Sophie, et al.
Publicado: (2022)

Systemically administered anti-TNF therapy ameliorates functional outcomes after focal cerebral ischemia
por: Clausen, Bettina Hjelm, et al.
Publicado: (2014)

Review: Tissue Engineering of Small-Diameter Vascular Grafts and Their In Vivo Evaluation in Large Animals and Humans
por: Fang, Shu, et al.
Publicado: (2021)

Spontaneous ischaemic stroke lesions in a dog brain: neuropathological characterisation and comparison to human ischaemic stroke
por: Thomsen, Barbara Blicher, et al.
Publicado: (2017)

Disturbed microcirculation and hyperaemic response in a murine model of systemic inflammation
por: Fruekilde, Signe Kirk, et al.
Publicado: (2022)

Cell therapy centered on IL-1Ra is neuroprotective in experimental stroke
por: Clausen, Bettina Hjelm, et al.
Publicado: (2016)

Interleukin-1beta and tumor necrosis factor-alpha are expressed by different subsets of microglia and macrophages after ischemic stroke in mice
por: Clausen, Bettina H, et al.
Publicado: (2008)

Acute Neurofilament Light Chain Plasma Levels Correlate With Stroke Severity and Clinical Outcome in Ischemic Stroke Patients
por: Nielsen, Helle H., et al.
Publicado: (2020)

Selective inhibition of soluble tumor necrosis factor signaling reduces abdominal aortic aneurysm progression
por: Griepke, Silke, et al.
Publicado: (2022)

Phytochemicals as inhibitors of tumor necrosis factor alpha and neuroinflammatory responses in neurodegenerative diseases
por: Zahedipour, Fatemeh, et al.
Publicado: (2022)

Apex Resection in Zebrafish (Danio rerio) as a Model of Heart Regeneration: A Video-Assisted Guide
por: Ellman, Ditte Gry, et al.
Publicado: (2021)

Decellularised Human Umbilical Artery as a Vascular Graft Elicits Minimal Pro-Inflammatory Host Response Ex Vivo and In Vivo
por: Ahlmann, Alexander Høgsted, et al.
Publicado: (2021)

A search for exotic decay modes on the proton drip-line - the cases of $^{20-21}$Mg
por: Lund, Morten Vinther
Publicado: (2016)

Effect of Oral Intake of Carrot Juice on Cyclooxygenases and Cytokines in Healthy Human Blood Stimulated by Lipopolysaccharide
por: Deding, Ulrik, et al.
Publicado: (2023)

Leukocyte TNFR1 and TNFR2 Expression Contributes to the Peripheral Immune Response in Cases with Ischemic Stroke
por: Hansen, Rikke B., et al.
Publicado: (2021)

Neuroinflammatory Process Involved in Different Preclinical Models of Chemotherapy-Induced Peripheral Neuropathy
por: Fumagalli, Giulia, et al.
Publicado: (2021)

Central but not systemic administration of XPro1595 is therapeutic following moderate spinal cord injury in mice
por: Novrup, Hans G, et al.
Publicado: (2014)

Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model
por: Bøttger, Pernille, et al.
Publicado: (2016)

Inhibition of astroglial NF-kappaB enhances oligodendrogenesis following spinal cord injury
por: Bracchi-Ricard, Valerie, et al.
Publicado: (2013)

Choroid plexus tumor necrosis factor receptor 1: a new neuroinflammatory piece of the complex Alzheimer’s disease puzzle
por: Steeland, Sophie, et al.
Publicado: (2019)

Maternal and fetal recovery after severe respiratory failure due to influenza: a case report
por: Madsen, Kristine, et al.
Publicado: (2013)

Ploidy-stratified single cardiomyocyte transcriptomics map Zinc Finger E-Box Binding Homeobox 1 to underly cardiomyocyte proliferation before birth
por: Bak, Sara Thornby, et al.
Publicado: (2023)

Vorinostat in the acute neuroinflammatory form of X‐linked adrenoleukodystrophy
por: Zierfuss, Bettina, et al.
Publicado: (2020)

Modelling neuroinflammatory phenotypes in vivo
por: Buckwalter, Marion S, et al.
Publicado: (2004)

Cannabinoid Modulation of Neuroinflammatory Disorders
por: Saito, Viviane M, et al.
Publicado: (2012)

Neuroinflammatory responses in diabetic retinopathy
por: Yu, Ying, et al.
Publicado: (2015)

Inflammasomes in neuroinflammatory and neurodegenerative diseases
por: Voet, Sofie, et al.
Publicado: (2019)

Neuroinflammatory and Demyelinating Disorders of Childhood
por: Nouri, Maryam Nabavi, et al.
Publicado: (2020)

Glia Crosstalk in Neuroinflammatory Diseases
por: Bernaus, Ada, et al.
Publicado: (2020)

The Neuroinflammatory Role of Pericytes in Epilepsy
por: Yamanaka, Gaku, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_am1midln2oovgg41tl9ocu3ktt