Cargando…

Evaluation of Pharmacokinetics and Safety with Bioequivalence of Ibuprofen Sustained-Release Capsules of Two Formulations, in Chinese Healthy Volunteers: Bioequivalence Study

PURPOSE: Ibuprofen is the first of the nonsteroidal anti-inflammatory drug (NSAID) to be used in the clinic. Our aim was to explore the pharmacokinetics (PK), bioequivalence, food effect, and safety of oral ibuprofen sustained-release capsules by two sponsors in healthy volunteers (HVs). METHODS: Tw...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Chunqi, Yin, Zhou, Yang, Yeqing, Mo, Nan, Yang, Hui, Wang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295470/
https://www.ncbi.nlm.nih.gov/pubmed/37384214
http://dx.doi.org/10.2147/DDDT.S404756