High Heme and Low Heme Oxygenase-1 Are Associated with Mast Cell Activation/Degranulation in HIV-Induced Chronic Widespread Pain

An overwhelming number of people with HIV (PWH) experience chronic widespread pain (CWP) throughout their lifetimes. Previously, we demonstrated that PWH with CWP have increased hemolysis and attenuated heme oxygenase 1 (HO-1) levels. HO-1 degrades reactive, cell-free heme into antioxidants like bil...

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Detalles Bibliográficos
Autores principales: Chatterjee, Tanima, Arora, Itika, Underwood, Lilly, Gryshyna, Anastasiia, Lewis, Terry L., Masjoan Juncos, Juan Xavier, Goodin, Burel R., Heath, Sonya, Aggarwal, Saurabh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295513/
https://www.ncbi.nlm.nih.gov/pubmed/37371943
http://dx.doi.org/10.3390/antiox12061213

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